Comparing the use of aggregate data and various methods of integrating individual patient data to network meta-analysis and its application to first-line ART

Comparing the use of aggregate data and various methods of integrating individual patient data to network meta-analysis and its application to first-line ART

Abstract Background The 2018 World Health Organization HIV guidelines were based on the results of a network meta-analysis (NMA) of published trials. This study employed individual patient-level data (IPD) and aggregate data (AgD) and meta-regression methods to assess the evidence supporting the WHO...

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Bibliographic Details
Main Authors: Steve Kanters, Mohammad Ehsanul Karim, Kristian Thorlund, Aslam H. Anis, Michael Zoratti, Nick Bansback
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Medical Research Methodology
Subjects:
Individual patient data
IPD
Network meta-analyses
One-stage NMA
Two-stage NMA
Ecological fallacy
Online Access:https://doi.org/10.1186/s12874-021-01254-5

Internet

https://doi.org/10.1186/s12874-021-01254-5

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