<i>HLA-DRB1*07:01</i> and *<i>08:02</i> Alleles Confer a Protective Effect Against ACPA-Positive Rheumatoid Arthritis in a Latin American Admixed Population

<i>HLA-DRB1*07:01</i> and *<i>08:02</i> Alleles Confer a Protective Effect Against ACPA-Positive Rheumatoid Arthritis in a Latin American Admixed Population

<i>HLA-DRB1</i> shared epitope (SE) alleles are important genetic contributors for the risk of developing anti-citrullinated protein antibodies (ACPA)-positive rheumatoid arthritis (RA), particularly in Caucasians. We aimed to analyze the contribution of HLA-DRB1 alleles and single nucle...

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Bibliographic Details
Main Authors: Patricia Castro-Santos, Jordi Olloquequi, Ricardo A. Verdugo, Miguel A. Gutiérrez, Carmen Pinochet, Luis A. Quiñones, Roberto Díaz-Peña
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Biology
Subjects:
HLA
HLA-DRB1
rheumatoid arthritis
ACPA
Latin American
admixed population
Online Access:https://www.mdpi.com/2079-7737/9/12/467

Internet

https://www.mdpi.com/2079-7737/9/12/467

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