Phorate triggers oxidative stress and mitochondrial dysfunction to enhance micronuclei generation and DNA damage in human lymphocytes

Herein, we studied phorate for its toxicological effects in human lymphocytes. Phorate treatment for 3 h has induced significant increase in the lymphocytic DNA damage. Compared to control, comet data from highest concentration of phorate (1000 µM) showed 8.03-fold increase in the Olive tail moment...

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Bibliographic Details
Main Authors: Quaiser Saquib, Mohammad Faisal, Sabiha Mahmood Ansari, Rizwan Wahab
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Saudi Journal of Biological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1319562X1930052X