Determination of galantamine in human plasma by LC-MS/MS using carbamazepine as an internal standard: Method validation and application to a pharmacokinetic study of galantamine hydrobromide prolonged-release capsules in healthy Thai volunteers

Determination of galantamine in human plasma by LC-MS/MS using carbamazepine as an internal standard: Method validation and application to a pharmacokinetic study of galantamine hydrobromide prolonged-release capsules in healthy Thai volunteers

A rapid, sensitive and reliable LC-MS/MS method for the determination of galantamine in plasma was developed and validated for the pharmacokinetic study of galantamine hydrobromide 8 mg prolonged-release capsules. The plasma sample was prepared by simple liquid-liquid extraction with dichloromethane...

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Bibliographic Details
Main Authors: Darunee Hongwiset, Songwut Yotsawimonwat, Chokchai Wongsinsup, Saowarunee Sangsrijan, Chuleegone Sornsuvit
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Cogent Medicine
Subjects:
galantamine
lc-ms/ms
human plasma
validation
pharmacokinetic study
Online Access:http://dx.doi.org/10.1080/2331205X.2020.1804093

Internet

http://dx.doi.org/10.1080/2331205X.2020.1804093

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