Pocket proteins critically regulate cell cycle exit of the trabecular myocardium and the ventricular conduction system

Pocket proteins critically regulate cell cycle exit of the trabecular myocardium and the ventricular conduction system

Summary During development, the ventricular conduction system (VCS) arises from the trabecular or spongy myocardium. VCS and trabecular myocytes proliferate at a significantly slower rate than compact zone myocardial cells, establishing a transmural cell cycle gradient. The molecular determinants of...

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Bibliographic Details
Main Authors: David S. Park, Rose O. Tompkins, Fangyu Liu, Jie Zhang, Colin K. L. Phoon, Jiri Zavadil, Glenn I. Fishman
Format: Article
Language:English
Published: The Company of Biologists 2013-07-01
Series:Biology Open
Subjects:
Cardiac conduction system
Cardiogenesis
Cell cycle
Chamber development
Pocket proteins
Trabecular myocardium
Online Access:http://bio.biologists.org/content/2/9/968

Internet

http://bio.biologists.org/content/2/9/968

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