Targeting Leukemia Stem Cells in the Bone Marrow Niche

The bone marrow (BM) niche encompasses multiple cells of mesenchymal and hematopoietic origin and represents a unique microenvironment that is poised to maintain hematopoietic stem cells. In addition to its role as a primary lymphoid organ through the support of lymphoid development, the BM hosts va...

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Bibliographic Details
Main Authors: Sarah K. Tasian, Martin Bornhäuser, Sergio Rutella
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Biomedicines
Subjects:
Online Access:http://www.mdpi.com/2227-9059/6/1/22