Identification of sVSG117 as an immunodiagnostic antigen and evaluation of a dual-antigen lateral flow test for the diagnosis of human African trypanosomiasis.

The diagnosis of human African trypanosomiasis (HAT) caused by Trypanosoma brucei gambiense relies mainly on the Card Agglutination Test for Trypanosomiasis (CATT). There is no immunodiagnostic for HAT caused by T. b. rhodesiense. Our principle aim was to develop a prototype lateral flow test that m...

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Bibliographic Details
Main Authors: Lauren Sullivan, Jennifer Fleming, Lalitha Sastry, Angela Mehlert, Steven J Wall, Michael A J Ferguson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-07-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4102454?pdf=render