Precision design of stable genetic circuits carried in highly‐insulated E. coli genomic landing pads

Abstract Genetic circuits have many applications, from guiding living therapeutics to ordering process in a bioreactor, but to be useful they have to be genetically stable and not hinder the host. Encoding circuits in the genome reduces burden, but this decreases performance and can interfere with n...

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Bibliographic Details
Main Authors: Yongjin Park, Amin Espah Borujeni, Thomas E Gorochowski, Jonghyeon Shin, Christopher A Voigt
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.15252/msb.20209584