Macrophage autophagy protects against hepatocellular carcinogenesis in mice

Abstract Autophagy is a lysosomal degradation pathway of cellular components that regulates macrophage properties. Macrophages are critically involved in tumor growth, metastasis, angiogenesis and immune suppression. Here, we investigated whether macrophage autophagy may protect against hepatocellul...

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Bibliographic Details
Main Authors: Anthony Deust, Marie-Noële Chobert, Vanessa Demontant, Guillaume Gricourt, Timothé Denaës, Allan Thiolat, Isaac Ruiz, Christophe Rodriguez, Jean-Michel Pawlotsky, Fatima Teixeira-Clerc
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-98203-5