Dynamic Changes of DNA Methylation and Transcriptome Expression in Porcine Ovaries during Aging

The biological function of human ovaries declines along with aging. To identify the underlying molecular changes during ovarian aging, pigs were used as model animals. Genome-wide DNA methylation and transcriptome-wide RNA expression analyses were performed via high-throughput sequencing of ovaries...

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Bibliographic Details
Main Authors: Xiaoyu Xi, Qin Zou, Yingying Wei, Yan Chen, Xue Wang, Daojun Lv, Peilin Li, Anxiang Wen, Li Zhu, Guoqing Tang, Jideng Ma, Mingzhou Li, Xuewei Li, Yanzhi Jiang
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2019/8732023