Faster embryonic segmentation through elevated Delta-Notch signalling

Rhythmic patterning governs the formation of somites in vertebrates, but how the period of such rhythms can be changed is unclear. Here, the authors generate a genetic model in zebrafish to increase DeltaD expression, which increases the range of Delta-Notch signalling, causing faster segmentation.

Bibliographic Details
Main Authors: Bo-Kai Liao, David J. Jörg, Andrew C. Oates
Format: Article
Language:English
Published: Nature Publishing Group 2016-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11861