Schizophrenia risk variants modulate white matter volume across the psychosis spectrum: Evidence from two independent cohorts

Schizophrenia risk variants modulate white matter volume across the psychosis spectrum: Evidence from two independent cohorts

Polygenic risk scores, based on risk variants identified in genome-wide-association-studies (GWAS), explain a considerable portion of the heritability for schizophrenia (SZ) and bipolar disorder (BD). However, little is known about the combined effects of these variants, although polygenic neuroima...

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Bibliographic Details
Main Authors: Viola Oertel-Knöchel, Thomas M. Lancaster, Christian Knöchel, Michael Stäblein, Helena Storchak, Britta Reinke, Alina Jurcoane, Jonathan Kniep, David Prvulovic, Kiran Mantripragada, Katherine E. Tansey, Michael C. O’Donovan, Michael J. Owen, David E.J. Linden
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:NeuroImage: Clinical
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158215000479

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http://www.sciencedirect.com/science/article/pii/S2213158215000479

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