Tackling Missing Heritability by Use of an Optimum Curve: A Systematic Review and Meta-Analysis

Tackling Missing Heritability by Use of an Optimum Curve: A Systematic Review and Meta-Analysis

Missing heritability is a common problem in psychiatry that impedes precision medicine approaches to autism and other heritable complex disorders. This proof-of-concept study uses a systematic review and meta-analysis of the association between variants of the serotonin transporter promoter (5-HTTLP...

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Bibliographic Details
Main Authors: Anneke Wegener Sleeswijk, Reinout Heijungs, Sarah Durston
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
missing heritability
optimum curve
inverted u
genetic association
context-dependent risk variants
multifactorial variable
5-httlpr polymorphism
autism
systematic review
meta-analysis
Online Access:https://www.mdpi.com/1422-0067/20/20/5104

Internet

https://www.mdpi.com/1422-0067/20/20/5104

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