Rivaroxaban Effects Illustrate the Underestimated Importance of Activated Platelets in Thrombin Generation Assessed by Calibrated Automated Thrombography

Rivaroxaban Effects Illustrate the Underestimated Importance of Activated Platelets in Thrombin Generation Assessed by Calibrated Automated Thrombography

Background: The direct oral anticoagulant rivaroxaban inhibiting specifically activated factor X (FXa) causes delayed thrombin generation (TG) as measured by calibrated automated thrombography (CAT). The implications of these changes for assessing bleeding or residual prothrombotic risks of patients...

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Bibliographic Details
Main Authors: Stephanie Makhoul, Marina Panova-Noeva, Véronique Regnault, Wolfram Ruf, Philip Wenzel, Jeremy Lagrange
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Journal of Clinical Medicine
Subjects:
thrombin
platelets
factor xa inhibitor
phospholipids
Online Access:https://www.mdpi.com/2077-0383/8/11/1990

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https://www.mdpi.com/2077-0383/8/11/1990

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