Sulfa Resistance and Dihydropteroate Synthase Mutants in Recurrent Pneumocystis carinii Pneumonia

Sulfa Resistance and Dihydropteroate Synthase Mutants in Recurrent Pneumocystis carinii Pneumonia

Failure of sulfa or sulfone prophylaxis is associated with mutations in Pneumocystis carinii gene coding for dihydropteroate synthase (DHPS). The DHPS genotype was analyzed in AIDS patients who had two separate episodes of P. carinii pneumonia. The results suggest that DHPS mutations can be selected...

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Bibliographic Details
Main Authors: Aimable Nahimana, Meja Rabodonirina, Jannik Helweg-Larsen, Isabelle Meneau, Patrick Francioli, Jacques Bille, Philippe M. Hauser
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2003-07-01
Series:Emerging Infectious Diseases
Subjects:
Pneumocystis carinii
pneumonia
fungal typing
drug resistance
drug pressure
mutation
Online Access:https://wwwnc.cdc.gov/eid/article/9/7/02-0753_article

Internet

https://wwwnc.cdc.gov/eid/article/9/7/02-0753_article

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