A comprehensive promoter landscape identifies a novel promoter for CD133 in restricted tissues, cancers and stem cells

A comprehensive promoter landscape identifies a novel promoter for CD133 in restricted tissues, cancers and stem cells

PROM1 is the gene encoding prominin-1 or CD133, an important cell surface marker for the isolation of both normal and cancer stem cells. PROM1 transcripts initiate at a range of transcription start sites (TSS) associated with distinct tissue and cancer expression profiles. Using high resolution Cap...

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Bibliographic Details
Main Authors: Ramakrishna eSompallae, Oliver Marc Hofmann, Christopher A Maher, Craig eGedye, Andreas eBehren, Morana eVitezic, Carsten O Daub, Sylvie eDevalle, Otavia L Caballero, Piero eCarninci, Yoshihide eHayashizaki, Elizabeth R Lawlor, Jonathan eCebon, Winston eHide
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Genetics
Subjects:
Melanoma
Cancer stem cell
PROM1 protein
AC133 antigen
transcription start site
promoter regions
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00209/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00209/full

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