Photophysics of DFHBI bound to RNA aptamer Baby Spinach

Abstract The discovery of the GFP-type dye DFHBI that becomes fluorescent upon binding to an RNA aptamer, termed Spinach, led to the development of a variety of fluorogenic RNA systems that enable genetic encoding of living cells. In view of increasing interest in small RNA aptamers and the scarcity...

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Bibliographic Details
Main Authors: Nguyen Thuan Dao, Reinhard Haselsberger, Mai Thu Khuc, Anh Tuân Phan, Alexander A. Voityuk, Maria-Elisabeth Michel-Beyerle
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85091-y