Ablation of dynamin-related protein 1 promotes diabetes-induced synaptic injury in the hippocampus

Ablation of dynamin-related protein 1 promotes diabetes-induced synaptic injury in the hippocampus

Abstract Dynamin-related protein 1 (Drp1)-mediated mitochondrial dysfunction is associated with synaptic injury in the diabetic brain. However, the dysfunctional mitochondria by Drp1 deletion in the diabetic brain are poorly understood. Here, we investigated the effects of neuron-specific Drp1 delet...

Full description

Bibliographic Details
Main Authors: Gyeongah Park, Jong Youl Lee, Hye Min Han, Hyeong Seok An, Zhen Jin, Eun Ae Jeong, Kyung Eun Kim, Hyun Joo Shin, Jaewoong Lee, Dawon Kang, Hyun Joon Kim, Yong Chul Bae, Gu Seob Roh
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03723-7

Internet

https://doi.org/10.1038/s41419-021-03723-7

Similar Items