Integrating Network Pharmacology and Experimental Validation to Investigate the Effects and Mechanism of Astragalus Flavonoids Against Hepatic Fibrosis

Integrating Network Pharmacology and Experimental Validation to Investigate the Effects and Mechanism of Astragalus Flavonoids Against Hepatic Fibrosis

Hepatic fibrosis (HF) represents the excessive wound healing where an excess amount of connective tissues is formed within the liver, finally resulting in cirrhosis or even hepatocellular carcinoma (HCC). Therefore, it is significant to discover the efficient agents and components to treat HF, thus...

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Bibliographic Details
Main Authors: Lin An, Yuefang Lin, Leyan Li, Muyan Kong, Yanmei Lou, Jinjun Wu, Zhongqiu Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
flavonoids
Astragalus membranaceus (fisch) bunge
liver fibrosis
anti-inflammation
network pharmacology
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.618262/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.618262/full

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