Role of Granulocyte-Macrophage Colony-Stimulating Factor Production by T Cells during Mycobacterium tuberculosis Infection

Role of Granulocyte-Macrophage Colony-Stimulating Factor Production by T Cells during Mycobacterium tuberculosis Infection

Mice deficient for granulocyte-macrophage colony-stimulating factor (GM-CSF−/−) are highly susceptible to infection with Mycobacterium tuberculosis, and clinical data have shown that anti-GM-CSF neutralizing antibodies can lead to increased susceptibility to tuberculosis in otherwise healthy people....

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Bibliographic Details
Main Authors: Alissa C. Rothchild, Britni Stowell, Girija Goyal, Cláudio Nunes-Alves, Qianting Yang, Kadamba Papavinasasundaram, Christopher M. Sassetti, Glenn Dranoff, Xinchun Chen, Jinhee Lee, Samuel M. Behar, Liise-anne Pirofski
Format: Article
Language:English
Published: American Society for Microbiology 2017-10-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/5/e01514-17

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http://mbio.asm.org/cgi/content/full/8/5/e01514-17

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