Role of platelets and platelet receptors in cancer metastasis

Abstract The interaction of tumor cells with platelets is a prerequisite for successful hematogenous metastatic dissemination. Upon tumor cell arrival in the blood, tumor cells immediately activate platelets to form a permissive microenvironment. Platelets protect tumor cells from shear forces and a...

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Bibliographic Details
Main Author: Martin Schlesinger
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Journal of Hematology & Oncology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13045-018-0669-2