A Fat-Facets-Dscam1-JNK Pathway Enhances Axonal Growth in Development and after Injury

A Fat-Facets-Dscam1-JNK Pathway Enhances Axonal Growth in Development and after Injury

Injury to the adult central nervous systems (CNS) can result in severe long-term disability because damaged CNS connections fail to regenerate after trauma. Identification of regulators that enhance the intrinsic growth capacity of severed axons is a first step to restore function. Here, we conducte...

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Bibliographic Details
Main Authors: Marta Koch, Maya Nicolas, Marlen Zschaetzsch, Natalie de Geest, Annelies Claeys, Jiekun Yan, Matthew J. Morgan, Maria-Luise Erfurth, Matthew Holt, Dietmar Schmucker, Bassem A. Hassan
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Cellular Neuroscience
Subjects:
axonal growth
axonal injury
post-transcriptional reguylatiopn
Central nervous system
Drosophila melanogaster
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2017.00416/full

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http://journal.frontiersin.org/article/10.3389/fncel.2017.00416/full

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