Mouse cofactor of BRCA1 (Cobra1) is required for early embryogenesis.

Negative elongation factor (NELF) is a four-subunit protein complex conserved from Drosophila to humans. In vitro biochemical and tissue culture-based studies have demonstrated an important role of NELF in controlling RNA polymerase II (Pol II) pausing in transcription. However, the physiological si...

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Bibliographic Details
Main Authors: Asma Amleh, Sreejith J Nair, Jianlong Sun, Ann Sutherland, Paul Hasty, Rong Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2661135?pdf=render