Protein Tyrosine Phosphatase SHP-2 Is Positively Involved in Platelet-Derived Growth Factor–Signaling in Vascular Neointima Formation via the Reactive Oxygen Species–Related Pathway

Protein Tyrosine Phosphatase SHP-2 Is Positively Involved in Platelet-Derived Growth Factor–Signaling in Vascular Neointima Formation via the Reactive Oxygen Species–Related Pathway

The roles of Src homology domain 2–containing protein tyrosine phosphatase 2 (SHP-2) and its signaling in atherosclerosis have not been explored. Therefore, we investigated the roles of SHP-2 in the movement of rat aortic smooth muscle cells (RASMCs) and in the neointima formation of the carotid art...

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Bibliographic Details
Main Authors: Kyung-Jong Won, Hwan Myung Lee, Chang-Kwon Lee, Hai Yue Lin, Haerang Na, Ki Won Lim, Hui Yul Roh, Seobo Sim, Hyuk Song, Wahn Soo Choi, Seung Hyun Lee, Bokyung Kim
Format: Article
Language:English
Published: Elsevier 2011-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319307820

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http://www.sciencedirect.com/science/article/pii/S1347861319307820

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