Induction of Krüppel-Like Factor 4 Mediates Polymorphonuclear Neutrophil Activation in Streptococcus pneumoniae Infection

Induction of Krüppel-Like Factor 4 Mediates Polymorphonuclear Neutrophil Activation in Streptococcus pneumoniae Infection

The recruitment and activation of polymorphonuclear neutrophils (PMNs) are of central importance for the elimination of pathogens in bacterial infections. We investigated the Streptococcus pneumoniae-dependent induction of the transcription factor Krüppel-like factor (KLF) 4 in PMNs as a potential r...

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Bibliographic Details
Main Authors: Aritra Bhattacharyya, Toni Herta, Claudia Conrad, Doris Frey, Pedro García, Norbert Suttorp, Stefan Hippenstiel, Janine Zahlten
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Microbiology
Subjects:
infectious diseases
innate immunity
neutrophils
Krüppel-like factor 4
S. pneumoniae
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2020.582070/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2020.582070/full

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