MYC gene delivery to adult mouse utricles stimulates proliferation of postmitotic supporting cells in vitro.

The inner ears of adult humans and other mammals possess a limited capacity for regenerating sensory hair cells, which can lead to permanent auditory and vestibular deficits. During development and regeneration, undifferentiated supporting cells within inner ear sensory epithelia can self-renew and...

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Bibliographic Details
Main Authors: Joseph C Burns, James J Yoo, Anthony Atala, John D Jackson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3484123?pdf=render