Targeting the innate repair receptor to treat neuropathy

Abstract. The innate repair receptor (IRR) is a heteromer of the erythropoietin receptor and the β-common (CD131) receptor, which simultaneously activates anti-inflammatory and tissue repair pathways. Experimental data suggest that after peripheral nerve injury, the IRR is upregulated in the spinal...

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Bibliographic Details
Main Authors: Albert Dahan, Michael Brines, Marieke Niesters, Anthony Cerami, Monique van Velzen
Format: Article
Language:English
Published: Wolters Kluwer 2016-07-01
Series:PAIN Reports
Online Access:http://journals.lww.com/painrpts/fulltext/10.1097/PR9.0000000000000566