Targeting the innate repair receptor to treat neuropathy
Abstract. The innate repair receptor (IRR) is a heteromer of the erythropoietin receptor and the β-common (CD131) receptor, which simultaneously activates anti-inflammatory and tissue repair pathways. Experimental data suggest that after peripheral nerve injury, the IRR is upregulated in the spinal...
Main Authors: | Albert Dahan, Michael Brines, Marieke Niesters, Anthony Cerami, Monique van Velzen |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer
2016-07-01
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Series: | PAIN Reports |
Online Access: | http://journals.lww.com/painrpts/fulltext/10.1097/PR9.0000000000000566 |
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