Sirtuin1 activator SRT2183 suppresses glioma cell growth involving activation of endoplasmic reticulum stress pathway
Abstract Background Glioblastoma (GBM) is an extremely deadly form of brain cancer with limited treatment options and thus novel therapeutic modalities are necessary. Histone deacetylase inhibitors (HDACi) have demonstrated clinical and preclinical activities against GBM. (Silent mating type informa...
Main Authors: | Tian Ye, Liwen Wei, Ji Shi, Ke Jiang, Huizhe Xu, Lulu Hu, Lingkai Kong, Ye Zhang, Songshu Meng, Haozhe Piao |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-07-01
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Series: | BMC Cancer |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12885-019-5852-5 |
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