iPSC-Cardiomyocyte Models of Brugada Syndrome—Achievements, Challenges and Future Perspectives

iPSC-Cardiomyocyte Models of Brugada Syndrome—Achievements, Challenges and Future Perspectives

Brugada syndrome (BrS) is an inherited cardiac arrhythmia that predisposes to ventricular fibrillation and sudden cardiac death. It originates from oligogenic alterations that affect cardiac ion channels or their accessory proteins. The main hurdle for the study of the functional effects of those va...

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Bibliographic Details
Main Authors: Aleksandra Nijak, Johan Saenen, Alain J. Labro, Dorien Schepers, Bart L. Loeys, Maaike Alaerts
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
Brugada syndrome
inherited cardiac arrhythmia
induced pluripotent stem cells
iPSC-cardiomyocytes
electrophysiology
Online Access:https://www.mdpi.com/1422-0067/22/6/2825

Internet

https://www.mdpi.com/1422-0067/22/6/2825

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