Multilineage Differentiation for Formation of Innervated Skeletal Muscle Fibers from Healthy and Diseased Human Pluripotent Stem Cells

Multilineage Differentiation for Formation of Innervated Skeletal Muscle Fibers from Healthy and Diseased Human Pluripotent Stem Cells

Induced pluripotent stem cells (iPSCs) obtained by reprogramming primary somatic cells have revolutionized the fields of cell biology and disease modeling. However, the number protocols for generating mature muscle fibers with sarcolemmal organization using iPSCs remain limited, and partly mimic the...

Full description

Bibliographic Details
Main Authors: Kilian Mazaleyrat, Cherif Badja, Natacha Broucqsault, Raphaël Chevalier, Camille Laberthonnière, Camille Dion, Lyla Baldasseroni, Claire El-Yazidi, Morgane Thomas, Richard Bachelier, Alexandre Altié, Karine Nguyen, Nicolas Lévy, Jérôme D. Robin, Frédérique Magdinier
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cells
Subjects:
human induced pluripotent cells
differentiation
myoblasts
myotubes
motor neurons
satellite cells
Online Access:https://www.mdpi.com/2073-4409/9/6/1531

Internet

https://www.mdpi.com/2073-4409/9/6/1531

Similar Items