Ezrin enrichment on curved membranes requires a specific conformation or interaction with a curvature-sensitive partner

Ezrin enrichment on curved membranes requires a specific conformation or interaction with a curvature-sensitive partner

One challenge in cell biology is to decipher the biophysical mechanisms governing protein enrichment on curved membranes and the resulting membrane deformation. The ERM protein ezrin is abundant and associated with cellular membranes that are flat, positively or negatively curved. Using in vitro and...

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Bibliographic Details
Main Authors: Feng-Ching Tsai, Aurelie Bertin, Hugo Bousquet, John Manzi, Yosuke Senju, Meng-Chen Tsai, Laura Picas, Stephanie Miserey-Lenkei, Pekka Lappalainen, Emmanuel Lemichez, Evelyne Coudrier, Patricia Bassereau
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-09-01
Series:eLife
Subjects:
ezrin
membrane curvature
I-BAR domain proteins
ezrin-membrane interaction
cellular protrusions
phosphorylation
Online Access:https://elifesciences.org/articles/37262

Internet

https://elifesciences.org/articles/37262

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