The angiotensin II/AT1 receptor pathway mediates malaria-induced acute kidney injury.

Malaria-induced acute kidney injury (MAKI) is a life-threatening complication of severe malaria. Here, we investigated the potential role of the angiotensin II (Ang II)/AT1 receptor pathway in the development of MAKI. We used C57BL/6 mice infected by Plasmodium berghei ANKA (PbA-infected mice), a we...

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Bibliographic Details
Main Authors: Leandro S Silva, Diogo B Peruchetti, Rodrigo P Silva-Aguiar, Thiago P Abreu, Beatriz K A Dal-Cheri, Christina M Takiya, Mariana C Souza, Maria G Henriques, Ana Acacia S Pinheiro, Celso Caruso-Neves
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6133374?pdf=render