Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease

Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease

Summary: Alzheimer disease (AD) is a devastating neurological disease associated with progressive loss of mental skills and cognitive and physical functions whose etiology is not completely understood. Here, our goal was to simultaneously uncover novel and known molecular targets in the structured l...

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Bibliographic Details
Main Authors: José Fernández Navarro, Deborah L. Croteau, Aleksandra Jurek, Zaneta Andrusivova, Beimeng Yang, Yue Wang, Benjamin Ogedegbe, Tahira Riaz, Mari Støen, Claus Desler, Lene Juel Rasmussen, Tone Tønjum, Marie-Christine Galas, Joakim Lundeberg, Vilhelm A. Bohr
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:iScience
Subjects:
Cellular Neuroscience
Omics
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220307483

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http://www.sciencedirect.com/science/article/pii/S2589004220307483

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