Pharmacokinetic Principles and Their Application to Central Nervous System Tumors

Despite increasing knowledge of the biologic drivers of central nervous system tumors, most targeted agents trialed to date have not shown activity against these tumors in clinical trials. To effectively treat central nervous system tumors, an active drug must achieve and maintain an effective expos...

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Bibliographic Details
Main Authors: Joelle P. Straehla, Katherine E. Warren
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/12/10/948