An expanded global inventory of allelic variation in the most extremely polymorphic region of Plasmodium falciparum merozoite surface protein 1 provided by short read sequence data

An expanded global inventory of allelic variation in the most extremely polymorphic region of Plasmodium falciparum merozoite surface protein 1 provided by short read sequence data

Abstract Background Within Plasmodium falciparum merozoite surface protein 1 (MSP1), the N-terminal block 2 region is a highly polymorphic target of naturally acquired antibody responses. The antigenic diversity is determined by complex repeat sequences as well as non-repeat sequences, grouping into...

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Bibliographic Details
Main Authors: Harvey Aspeling-Jones, David J. Conway
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Malaria Journal
Subjects:
Polymorphism
msp1
Repeat sequences
Sequence mapping
De novo assembly
Molecular epidemiology
Online Access:http://link.springer.com/article/10.1186/s12936-018-2475-2

Internet

http://link.springer.com/article/10.1186/s12936-018-2475-2

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