Memory CD73+IgM+ B cells protect against Plasmodium yoelii infection and express Granzyme B.

To better understand anti-malaria protective immune responses, we examined the cellular mechanisms that govern protective immunity in a murine Plasmodium yoelii 17X NL (PyNL) re-infection model. Initially, we confirmed that immune B cells generated during a primary PyNL infection were largely respon...

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Bibliographic Details
Main Authors: Marcela Parra, Megan Weitner, Amy Yang, Adovi Akue, Xia Liu, Thomas Schmidt, Windy R Allman, Mustafa Akkoyunlu, Steven C Derrick
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0238493