A sufficient role of MHC class I molecules on hepatocytes in anti-plasmodial activity of CD8+ T cells in vivo

A sufficient role of MHC class I molecules on hepatocytes in anti-plasmodial activity of CD8+ T cells in vivo

Although CD8+ T cells are shown to mediate the protective immunity against the liver stages of malaria parasites in mice, whether the direct presentation of malaria antigen by major histocompatibility complex (MHC) class I molecules expressed on the liver of infected host is required for anti-plasmo...

Full description

Bibliographic Details
Main Authors: Jing eHuang, Tiffany eTsao, Min eZhang, Urvashi eRai, Moriya eTsuji, Xiangming eLi
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Microbiology
Subjects:
Liver
Malaria
MHC class I
CD8+ T cell
Transgenic mouse
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00069/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00069/full

Similar Items