Sequential broadening of CTL responses in early HIV-1 infection is associated with viral escape.

Sequential broadening of CTL responses in early HIV-1 infection is associated with viral escape.

BACKGROUND:Antigen-specific CTL responses are thought to play a central role in containment of HIV-1 infection, but no consistent correlation has been found between the magnitude and/or breadth of response and viral load changes during disease progression. METHODS AND FINDINGS:We undertook a detaile...

Full description

Bibliographic Details
Main Authors: Annika C Karlsson, Astrid K N Iversen, Joan M Chapman, Tulio de Oliviera, Gerald Spotts, Andrew J McMichael, Miles P Davenport, Frederick M Hecht, Douglas F Nixon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1790860?pdf=render

Internet

http://europepmc.org/articles/PMC1790860?pdf=render

Similar Items