Effects of Two Types of Melatonin-Loaded Nanocapsules with Distinct Supramolecular Structures: Polymeric (NC) and Lipid-Core Nanocapsules (LNC) on Bovine Embryo Culture Model.

Melatonin has been used as a supplement in culture medium to improve the efficiency of in vitro produced mammalian embryos. Through its ability to scavenge toxic oxygen derivatives and regulate cellular mRNA levels for antioxidant enzymes, this molecule has been shown to play a protective role again...

Full description

Bibliographic Details
Main Authors: Eliza Rossi Komninou, Mariana Härter Remião, Caroline Gomes Lucas, William Borges Domingues, Andrea Cristina Basso, Denise Soledade Jornada, João Carlos Deschamps, Ruy Carlos Ruver Beck, Adriana Raffin Pohlmann, Vilceu Bordignon, Fabiana Kömmling Seixas, Vinicius Farias Campos, Silvia Stanisçuaski Guterres, Tiago Collares
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4910990?pdf=render