Exogenous leptin affects sperm parameters and impairs blood testis barrier integrity in adult male mice

Exogenous leptin affects sperm parameters and impairs blood testis barrier integrity in adult male mice

Abstract Background Serum leptin levels are augmented in obese infertile men and in men with azoospermia. They also correlate inversely with sperm concentration, motility and normal forms. The mechanisms underlying the adverse effects of excess leptin on male reproductive function remain unclear. Th...

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Bibliographic Details
Main Authors: Xiaotong Wang, Xiaoke Zhang, Lian Hu, Honggang Li
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Reproductive Biology and Endocrinology
Subjects:
Obesity
Leptin
Male infertility
Mice
Sertoli cell
Blood testis barrier
Online Access:http://link.springer.com/article/10.1186/s12958-018-0368-4

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http://link.springer.com/article/10.1186/s12958-018-0368-4

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