Epidermal mTORC1 Signaling Contributes to the Pathogenesis of Psoriasis and Could Serve as a Therapeutic Target

Epidermal mTORC1 Signaling Contributes to the Pathogenesis of Psoriasis and Could Serve as a Therapeutic Target

Although modern biologics targeting different inflammatory mediators show promising therapeutic success, comprehensive knowledge about the molecular events in psoriatic keratinocytes that contribute to the pathogenesis and could serve as therapeutic targets is still scarce. However, recent efforts t...

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Bibliographic Details
Main Author: Claudia Buerger
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Immunology
Subjects:
psoriasis
mTORC1
keratinocytes
rapamycin
topical agent
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02786/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02786/full

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