MicroRNA-27a Contributes to Rhabdomyosarcoma Cell Proliferation by Suppressing RARA and RXRA.

Rhabdomyosarcomas (RMS) are rare but very aggressive childhood tumors that arise as a consequence of a regulatory disruption in the growth and differentiation pathways of myogenic precursor cells. According to morphological criteria, there are two major RMS subtypes: embryonal RMS (ERMS) and alveola...

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Bibliographic Details
Main Authors: Lucia Tombolan, Matteo Zampini, Silvia Casara, Elena Boldrin, Angelica Zin, Gianni Bisogno, Angelo Rosolen, Cristiano De Pittà, Gerolamo Lanfranchi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4410939?pdf=render