Naturally occurring variant of mouse apolipoprotein A-I alters the lipid and HDL association properties of the protein

Naturally occurring variant of mouse apolipoprotein A-I alters the lipid and HDL association properties of the protein

Plasma HDL levels are inversely associated with atherosclerosis. Inbred mouse strains differ in plasma HDL levels and susceptibility to atherosclerosis. Atherosclerosis-susceptible C57BL/6J mice possess plasma HDL levels 2-fold lower than atherosclerosis-resistant FVB/NJ mice. Polymorphisms have bee...

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Bibliographic Details
Main Authors: Timothy J. Sontag, Ronald Carnemolla, Tomas Vaisar, Catherine A. Reardon, Godfrey S. Getz
Format: Article
Language:English
Published: Elsevier 2012-05-01
Series:Journal of Lipid Research
Subjects:
cholesterol efflux
lipid binding
alpha helix
high density lipoprotein
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520392257

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http://www.sciencedirect.com/science/article/pii/S0022227520392257

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