The PI3K-Akt-mTOR Signaling Pathway in Human Acute Myeloid Leukemia (AML) Cells

The PI3K-Akt-mTOR Signaling Pathway in Human Acute Myeloid Leukemia (AML) Cells

Acute myeloid leukemia (AML) is a heterogeneous group of diseases characterized by uncontrolled proliferation of hematopoietic stem cells in the bone marrow. Malignant cell growth is characterized by disruption of normal intracellular signaling, caused by mutations or aberrant external signaling. Th...

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Bibliographic Details
Main Authors: Ina Nepstad, Kimberley Joanne Hatfield, Ida Sofie Grønningsæter, Håkon Reikvam
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
Akt
AML
chemotherapy
metabolism
mTOR
PI3K
Online Access:https://www.mdpi.com/1422-0067/21/8/2907

Internet

https://www.mdpi.com/1422-0067/21/8/2907

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