Haem iron reshapes colonic luminal environment: impact on mucosal homeostasis and microbiome through aldehyde formation

Haem iron reshapes colonic luminal environment: impact on mucosal homeostasis and microbiome through aldehyde formation

Abstract Background The World Health Organization classified processed and red meat consumption as “carcinogenic” and “probably carcinogenic”, respectively, to humans. Haem iron from meat plays a role in the promotion of colorectal cancer in rodent models, in association with enhanced luminal lipope...

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Bibliographic Details
Main Authors: Océane C. B. Martin, Maïwenn Olier, Sandrine Ellero-Simatos, Nathalie Naud, Jacques Dupuy, Laurence Huc, Sylviane Taché, Vanessa Graillot, Mathilde Levêque, Valérie Bézirard, Cécile Héliès-Toussaint, Florence Blas Y. Estrada, Valérie Tondereau, Yannick Lippi, Claire Naylies, Lindsey Peyriga, Cécile Canlet, Anne Marie Davila, François Blachier, Laurent Ferrier, Elisa Boutet-Robinet, Françoise Guéraud, Vassilia Théodorou, Fabrice H. F. Pierre
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Microbiome
Subjects:
Lipoperoxidation
Barrier function
Metabolites
Dysbiosis
Meat
Online Access:http://link.springer.com/article/10.1186/s40168-019-0685-7

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http://link.springer.com/article/10.1186/s40168-019-0685-7

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