Lineage space and the propensity of bacterial cells to undergo growth transitions.

The molecular makeup of the offspring of a dividing cell gradually becomes phenotypically decorrelated from the parent cell by noise and regulatory mechanisms that amplify phenotypic heterogeneity. Such regulatory mechanisms form networks that contain thresholds between phenotypes. Populations of ce...

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Bibliographic Details
Main Authors: Arnab Bandyopadhyay, Huijing Wang, J Christian J Ray
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-08-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1006380