Gametocytes of the Malaria Parasite Plasmodium falciparum Interact With and Stimulate Bone Marrow Mesenchymal Cells to Secrete Angiogenetic Factors

Gametocytes of the Malaria Parasite Plasmodium falciparum Interact With and Stimulate Bone Marrow Mesenchymal Cells to Secrete Angiogenetic Factors

The gametocytes of Plasmodium falciparum, responsible for the transmission of this malaria parasite from humans to mosquitoes, accumulate and mature preferentially in the human bone marrow. In the 10 day long sexual development of P. falciparum, the immature gametocytes reach and localize in the ext...

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Bibliographic Details
Main Authors: Valeria Messina, Mauro Valtieri, Mercedes Rubio, Mario Falchi, Francesca Mancini, Alfredo Mayor, Pietro Alano, Francesco Silvestrini
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
malaria
gametocytes
bone marrow
host-pathogen interactions
angiogenesis
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2018.00050/full

Internet

http://journal.frontiersin.org/article/10.3389/fcimb.2018.00050/full

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