Gut-associated plasmacytoid dendritic cells display an immature phenotype and upregulated granzyme B in subjects with HIV/AIDS

Gut-associated plasmacytoid dendritic cells display an immature phenotype and upregulated granzyme B in subjects with HIV/AIDS

Plasmacytoid dendritic cells in the periphery of subjects with HIV/AIDS decrease over time and the fate of these cells has been the subject of ongoing investigation. Previous studies using animal models as well as studies with humans suggest that these cells may redistribute to the gut. Other studi...

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Bibliographic Details
Main Authors: Sergei V Boichuk, Svetlana F Khaiboullina, Bulat R Ramazanov, Gulshat R Khasanova, Karina A Ivanovskaya, Evgeny Z Nizamutdinov, Marat R Sharafutdinov, Ekaterina М Martynova, Kenny L DeMeirleir, Jan eHulstaert, Vladimir A Anokhin, Albert A Rizvanov, Vincent C Lombardi
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Immunology
Subjects:
gut
hiv/aids
granzyme B
pDc
plasmacytoid dendritic cell
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00485/full

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http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00485/full

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