Gene therapy for amyotrophic lateral sclerosis

Gene therapy for amyotrophic lateral sclerosis

Gene therapy continues to be a potential option for amyotrophic lateral sclerosis (ALS). This chapter will inform the reader about promising therapeutic transgenes and proof-of-principle studies in transgenic rodent models of ALS. Challenges regarding the disease targets and time for therapeutic int...

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Bibliographic Details
Main Authors: Thais Federici, Nicholas M. Boulis
Format: Article
Language:English
Published: Elsevier 2012-11-01
Series:Neurobiology of Disease
Subjects:
Astrocytes
Gene delivery
Motor neurons
Neurotrophic factors
RNA interference
Superoxide dismutase 1
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996111002841

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http://www.sciencedirect.com/science/article/pii/S0969996111002841

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